![]() ![]() Surgical resection is currently the most effective treatment method for colorectal liver metastasis (CRLM), with a 5-year survival rate of 40-50% 1. Patients with a smaller tumor burden are more likely to benefit from chemotherapy and achieve pCR. ![]() Liver metastases <3 cm, preoperative carcinoembryonic antigen level ≤20 ng/mL, primary T stage 1-2, and right-sided primary tumors were independent predictors for pCR.Ĭonclusion: pCR occurred in 6% of patients with CRLM after preoperative chemotherapy. The long-term prognosis of patients with pCR was extremely favorable, with 10-year overall and disease-free survivals of 85.2% and 73.7%, respectively these were significantly better than those of patients without pCR (31.3% and 15.2%, respectively). Results: Thirty (6.07%) patients achieved pCR after preoperative chemotherapy 70% patients who achieved pCR did not experience recurrence and were cured after hepatectomy. pCR was defined as the absence of any cancer cells on pathological examination. Methods: We retrospectively analyzed the clinical data of 494 CRLM patients who underwent hepatectomy after preoperative chemotherapy between January 2006 and January 2019. ![]() This study aimed to explore the characteristics and long-term survival of CRLM patients with pCR, who underwent surgery after preoperative chemotherapy. Pathological complete response (PCR) after chemotherapy indicates complete tumor regression and an extremely favorable prognosis. Purpose: Preoperative chemotherapy is widely used for colorectal liver metastasis (CRLM). ![]()
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